Sulfamethoxazole with Trimethoprim (sulfa-meth-ox�-ah-zole tri-meth�-o-prim)
Bactrim (Roche), Septra (Monarch)
What is this medication used for
Sulfamethoxazole with trimethoprim is a potentiated sulfonamide
with antibacterial properties. It is used to treat bacterial infections
of the lungs, urinary tract, skin and gastrointestinal organs caused
by susceptible organisms
Sulfamethoxazole with trimethoprim is available by prescription
as tablets and suspension.
How this medicine should be used
Sulfamethoxazole with trimethoprim is not FDA approved for use in
veterinary medicine; however, it is a commonly accepted practice
for veterinarians to use this medication in dogs and cats. The usual
dose in dogs and cats is 13mg/pound every 24 hours which may be
divided into two doses 12 hours apart.
What are the side effects
Side effects when using sulfamethoxazole with trimethoprim may include
loss of appetite, vomiting, diarrhea, fever, anemia, allergic reaction
including facial swelling and hives, and seizures. Eyes should be
monitored for KCS (dry eyes).
What special precautions are there
Do not use sulfamethoxazole with trimethoprim in animals allergic
to it or other sulfonamides (sulfa drugs). Do not use in animals
with liver or kidney disease or blood disorders. Do not use in pregnant
or nursing animals. The animal must be allowed to drink a lot of
water. Use caution when giving with methotrexate, phenylbutazone,
salicylates, probenecid, phenytoin, anticoagulants such as warfarin
and MAOIs such as selegiline. Always tell your veterinarian and
pharmacist what other medications your pet is taking. If using the
suspension, shake well before each use.
In the event of an overdose
Contact your veterinarian or veterinary emergency room. Symptoms
of overdose while rare may include vomiting, diarrhea or hyperexcitability.
How should I store this medication
Keep this medication in the container it came in, tightly closed.
Store this medication at room temperature, away from excess heat,
light and moisture. Do not store in the bathroom. Throw away any
medication that is outdated or no longer needed. Keep this medication
out of the reach of children and pets.
This information sheet is for educational purposes only and is
intended to be a supplement to, and not a substitute for, the expertise
and professional judgment of your veterinarian. The information
is NOT to be used for diagnosis or treatment of your pet. You should
always consult your own veterinarian for specific advice concerning
the treatment of your pet.
The information is not intended to cover all possible uses, directions,
precautions, warnings, allergic reactions, drug interactions or
adverse effects, nor should it be construed to indicate that use
of a particular drug is safe, appropriate or effective for your
pet. It is not a substitute for a veterinary exam, and it does not
replace the need for services provided by your veterinarian.
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