Non steroidal option for long term care of canine dermatitis. Reduces
itching 45% and skin lesions 67%.
Cyclosporine (sy-klo-spor’-een) Modified capsule
Novartis Animal Health
What is this medication used for
Cyclosporine Modified capsule is a selective immunomodulator. It
is used for the treatment of atopic dermatitis in dogs.
Cyclosporine Modified capsule is a prescription medication available
as oral soft capsules packaged in blister packs.
How this medication should be used
Cyclosporine Modified capsule is FDA approved for use in veterinary
medicine for dogs at least 6 months of age and at least 4.5 lbs.
The usual dose is 2.5mg/pound. Dogs 4-6.5lbs give 1 x 10mg capsule,
6.6-9lbs give 2 x 10mg capsules, 9.1-16lbs give 1 x 25mg capsule,
16.1-33lbs give 1 x 50mg capsule, 33.1-64lbs give 1 x 100mg capsule,
64.1-79lbs give 1 x 100mg and 1 x 50mg capsules and for dogs 79.1-121lbs
give 2 x 100mg capsules. The medication should be given 2 hours
before or after feeding. Cyclosporine Modified is initially given
once a day until satisfactory improvement is seen, usually 4 to
8 weeks. The medication can then be given every other day until
the clinical signs of atopic dermatitis are satisfactorily controlled,
then the medication can be given every 3 to 4 days.
What are the side effects
Side effects of Cyclosporine Modified capsule include GI disturbances
such as vomiting, soft stool or diarrhea. These symptoms are usually
mild and transient. Other side effects that occur very rarely include,
muscle cramps, muscle weakness, loss of appetite, gingival hypertrophy
and change of hair coat.
What special precautions are there
The safety of use in breeding, pregnant or lactating dogs has not
been determined. It should not be used in dogs with known hypersensitivity
or allergy to the drug. The drug should be avoided in dogs with
kidney impairment, stomach ulcers and certain blood disorders. Prolonged
use of Cyclosporine Modified can result in bacterial or fungal infection
related to deficiency of the immune system. Cyclosporine Modified
may decrease the immune response in case of malignancy. Cyclosporine
Modified may interact with other medications such as ACE inhibitors,
phenobarbital, cimetidine, cisapride, systemic coticosteroids, digoxin,
griseofulvin, metoclopramide, metronidazole, NSAIDS, phenytoin,
potassium salts, and Ketoconazole. The medication is bitter. Do
not empty the contents of the capsule.
In the event of an overdose
Contact your veterinarian or veterinary emergency room.
How should I store the medication
Each card consists of a blister pack with 15 capsules. The capsule
should be left in the blister until required for use. When removed
from the blister there is a characteristic, noticeable smell which
is normal. Store at room temperature away from excess heat, light
and moisture. Do not store in the bathroom. Keep out of the reach
of children and pets.
This information sheet is for educational purposes only and is
intended to be a supplement to, and not a substitute for, the expertise
and professional judgment of your veterinarian. The information
is NOT to be used for diagnosis or treatment of your pet. You should
always consult your own veterinarian for specific advice concerning
the treatment of your pet.
The information is not intended to cover all possible uses, directions,
precautions, warnings, allergic reactions, drug interactions or
adverse effects, nor should it be construed to indicate that use
of a particular drug is safe, appropriate or effective for your
pet. It is not a substitute for a veterinary exam, and it does not
replace the need for services provided by your veterinarian.
Note: Any trademarks are the property of their respective companies
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