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Non steroidal option for long term care of canine dermatitis. Reduces itching 45% and skin lesions 67%.

Generic Name
Cyclosporine (sy-klo-spor’-een) Modified capsule

Novartis Animal Health

Brand Name(s)

What is this medication used for
Cyclosporine Modified capsule is a selective immunomodulator. It is used for the treatment of atopic dermatitis in dogs.

Cyclosporine Modified capsule is a prescription medication available as oral soft capsules packaged in blister packs.

How this medication should be used
Cyclosporine Modified capsule is FDA approved for use in veterinary medicine for dogs at least 6 months of age and at least 4.5 lbs. The usual dose is 2.5mg/pound. Dogs 4-6.5lbs give 1 x 10mg capsule, 6.6-9lbs give 2 x 10mg capsules, 9.1-16lbs give 1 x 25mg capsule, 16.1-33lbs give 1 x 50mg capsule, 33.1-64lbs give 1 x 100mg capsule, 64.1-79lbs give 1 x 100mg and 1 x 50mg capsules and for dogs 79.1-121lbs give 2 x 100mg capsules. The medication should be given 2 hours before or after feeding. Cyclosporine Modified is initially given once a day until satisfactory improvement is seen, usually 4 to 8 weeks. The medication can then be given every other day until the clinical signs of atopic dermatitis are satisfactorily controlled, then the medication can be given every 3 to 4 days.

What are the side effects
Side effects of Cyclosporine Modified capsule include GI disturbances such as vomiting, soft stool or diarrhea. These symptoms are usually mild and transient. Other side effects that occur very rarely include, muscle cramps, muscle weakness, loss of appetite, gingival hypertrophy and change of hair coat.

What special precautions are there
The safety of use in breeding, pregnant or lactating dogs has not been determined. It should not be used in dogs with known hypersensitivity or allergy to the drug. The drug should be avoided in dogs with kidney impairment, stomach ulcers and certain blood disorders. Prolonged use of Cyclosporine Modified can result in bacterial or fungal infection related to deficiency of the immune system. Cyclosporine Modified may decrease the immune response in case of malignancy. Cyclosporine Modified may interact with other medications such as ACE inhibitors, phenobarbital, cimetidine, cisapride, systemic coticosteroids, digoxin, griseofulvin, metoclopramide, metronidazole, NSAIDS, phenytoin, potassium salts, and Ketoconazole. The medication is bitter. Do not empty the contents of the capsule.

In the event of an overdose
Contact your veterinarian or veterinary emergency room.

How should I store the medication
Each card consists of a blister pack with 15 capsules. The capsule should be left in the blister until required for use. When removed from the blister there is a characteristic, noticeable smell which is normal. Store at room temperature away from excess heat, light and moisture. Do not store in the bathroom. Keep out of the reach of children and pets.

This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet.

The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian.

Note: Any trademarks are the property of their respective companies

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