Cefpodoxime (sef-poe-dock�-seem) proxetil
Simplicef (Pfizer Animal Health), Vantin (Pharmacia and Upjohn)
What is this medication used for
Simplicef is a cephalosporin antibiotic indicated for use in the
treatment of skin infections (wounds and abscesses) of dogs caused
by susceptible strains of bacteria.
Simplicef is available by prescription as 100mg scored tablets and
How this medication should be used
Simplicef is FDA approved for use in veterinary medicine. The usual
dose in dogs is 2.3-4.5mg per lb, given by mouth, once a day for
5 to 7 days or 2 to 3 days beyond the cessation of clinical signs,
up to a maximum of 28 days. The actual dose and duration of therapy
is based on the particular infection and the dog�s response to treatment.
What are the side effects
Side effects of Simplicef may include vomiting, diarrhea and decreased
What special precautions are there
This medication should not be used in animals allergic to it or
other penicillins or cephalosporins. Use with caution in breeding,
pregnant or lactating dogs. Use with caution in animals with impaired
kidney function. Use with caution in animals with seizure disorder.
This medication is for animal use only.
In the event of overdose
Contact your veterinarian or veterinary emergency room.
How should I store this medication
Keep this medication in the container it came in, tightly closed.
Store the tablets at room temperature (68� to 77� F), away from
excess heat, light and moisture. Do not store in the bathroom. Throw
away any medication that is outdated or no longer needed. Keep this
medication out of the reach of children and pets.
This information sheet is for educational purposes only and is
intended to be a supplement to, and not a substitute for, the expertise
and professional judgment of your veterinarian. The information
is NOT to be used for diagnosis or treatment of your pet. You should
always consult your own veterinarian for specific advice concerning
the treatment of your pet.
The information is not intended to cover all possible uses, directions,
precautions, warnings, allergic reactions, drug interactions or
adverse effects, nor should it be construed to indicate that use
of a particular drug is safe, appropriate or effective for your
pet. It is not a substitute for a veterinary exam, and it does not
replace the need for services provided by your veterinarian.
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